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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: mahayoub on November 14, 2012, 01:10:46 PM

Title: Gel filtration chromatography
Post by: mahayoub on November 14, 2012, 01:10:46 PM
Hello everyone   :)

I am going to work on protein hydrolysis in the seed dates, but I search many times about how to pack the gel filtration chromatography and I couldnt find a good answer. I need this for my proposal research. I want to know the experiment and how to pack the column in order to fraction proteins according to their sizes.

Thanks
Title: Re: Gel filtration chromatography
Post by: discodermolide on November 14, 2012, 01:12:42 PM
Shall we write the research proposal for you? It would save time.
Title: Re: Gel filtration chromatography
Post by: Arkcon on November 14, 2012, 02:19:39 PM
You may find a good laboratory text, or you might find a simple handbook around the lab--vendors create these, to teach people how to use the stuff they sell.  Like discodermolide: has alluded to, you have asked too general a question.  What, in your vast array of search results, have you read, that you don't understand, or are unsure of which options to take?
Title: Re: Gel filtration chromatography
Post by: mahayoub on November 14, 2012, 03:31:57 PM
Shall we write the research proposal for you? It would save time.

Thanks for helping
Title: Re: Gel filtration chromatography
Post by: mahayoub on November 14, 2012, 03:34:15 PM
You may find a good laboratory text, or you might find a simple handbook around the lab--vendors create these, to teach people how to use the stuff they sell.  Like discodermolide: has alluded to, you have asked too general a question.  What, in your vast array of search results, have you read, that you don't understand, or are unsure of which options to take?

Yes, i am unsure which options I have to take. I just want to know the basic method to prepare the column according to my topic. Thank you  :)
Title: Re: Gel filtration chromatography
Post by: Babcock_Hall on November 14, 2012, 06:32:58 PM
I suggest you read pages 125-133 in Fundamental Laboratory Approaches for Biochemistry and Biotechnology, by Ninfa, Ballou, and Benore, 2nd edition, Wiley.  You might also try Pharmacia's book "Gel Filtration:  Principles and Methods", which is available as a free pdf download from Amersham Biosciences.
Title: Re: Gel filtration chromatography
Post by: mahayoub on November 14, 2012, 10:34:36 PM
I suggest you read pages 125-133 in Fundamental Laboratory Approaches for Biochemistry and Biotechnology, by Ninfa, Ballou, and Benore, 2nd edition, Wiley.  You might also try Pharmacia's book "Gel Filtration:  Principles and Methods", which is available as a free pdf download from Amersham Biosciences.

Thank you. The books are very useful.  :)