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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: darkdevil on October 01, 2015, 11:49:58 AM

Title: About Click Chemistry
Post by: darkdevil on October 01, 2015, 11:49:58 AM

Hi,
I read a lot of literatures about the click chemistry between an alkyne and an azide. I just wonder if it is possible for alkene and azide to undergo such cycloaddition reaction?

Title: Re: About Click Chemistry
Post by: TheUnassuming on October 01, 2015, 12:03:43 PM

Indeed it is, under certain circumstances. 

Check out this paper: J. Am. Chem. Soc. 2015, 137, 2958−2966