Chemical Forums
1 Hour
1 Day
1 Week
1 Month
Forever
December 22, 2024, 05:06:05 AM
Forum Rules
: Read This Before Posting
Home
Help
Search
Login
Register
Chemical Forums
Chemistry Forums for Students
Organic Chemistry Forum
Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
« previous
next »
Print
Pages: [
1
]
Go Down
Topic: Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3? (Read 1381 times)
0 Members and 1 Guest are viewing this topic.
AussieKenDoll
Full Member
Posts: 123
Mole Snacks: +0/-0
Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
«
on:
July 16, 2019, 10:18:36 AM »
Why Nucleophilic substitution of pyridine undergoes predominantly at C2 and C4 but not on C3, why?
Logged
spirochete
Chemist
Full Member
Posts: 547
Mole Snacks: +51/-9
Gender:
Re: Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
«
Reply #1 on:
July 16, 2019, 06:38:18 PM »
Draw the mechanism, including all resonance structures for the anionic intermediate. Then, think about them. Where is negative charge more stable in anions? That will explain it.
Logged
AussieKenDoll
Full Member
Posts: 123
Mole Snacks: +0/-0
Re: Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
«
Reply #2 on:
July 19, 2019, 11:20:05 AM »
the positive charge is on C2, C4 and C6 on the resonance structures? but I still do not understand why
Logged
Print
Pages: [
1
]
Go Up
« previous
next »
Sponsored Links
Chemical Forums
Chemistry Forums for Students
Organic Chemistry Forum
Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?