[levis123]

For reduction of aromatic nitro- group to amine, will Fe/NH4Cl in MeOH/H2O (and heat) affect my carboxylic acid on the ring?

From what I have read it won't be a problem, but I am not sure.

[OrganicDan96]

I can't see why it would

[levis123]

I can't see why it would

Ok, thank you. However, the article says i should extract it from DCM and wash it with water and brine, then concentrate the DCM. The procedure is for a compound without a carboxylic acid on. My compound is (according to lit.) very water soluble, so will it transfer into DCM or stay in the aqueous layer? Also, since mine is an acid, washing it with brine may produce the corresponding salt causing it to transfer into aqueous layer.

Can you suggest any other workup method?

Thanks in advance.