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Topic: How to do this organic conversion  (Read 1182 times)

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Offline AussieKenDoll

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How to do this organic conversion
« on: September 18, 2020, 05:47:07 AM »
I am not sure how to get the final -COH group and how to remove the -COOEt group from initial molecule?

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Offline AussieKenDoll

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Re: How to do this organic conversion
« Reply #1 on: September 18, 2020, 05:48:47 AM »
A should be NaOEt/EtOH i guess
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Offline Samirkher

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Re: How to do this organic conversion
« Reply #2 on: September 18, 2020, 01:37:49 PM »
You can alkylate using Br(CH)2(CH)2CHO then hydrolysis of Ester followed bydecorboxylation.
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Offline rolnor

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Re: How to do this organic conversion
« Reply #3 on: September 19, 2020, 10:06:02 AM »
Quote from: Samirkher on September 18, 2020, 01:37:49 PM
You can alkylate using Br(CH)2(CH)2CHO then hydrolysis of Ester followed bydecorboxylation.

What do you know about aldehydes and nucleophiles? And beta-halogenaldehydes and E1cb-mechanism, this is basic conditions?
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