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Topic: Crabbe Homologation  (Read 2009 times)

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Offline wuwusuxi

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Crabbe Homologation
« on: August 13, 2021, 03:54:36 AM »
Has anyone had success with this reaction?  I have a refrence below.  The material is racemic methyl-2-methylhex-5-ynoate.
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Offline rolnor

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Re: Crabbe Homologation
« Reply #1 on: August 14, 2021, 04:56:46 AM »
This is a very exotic reaction, low chance that someone here has done it. Are you going to use amine as reagent? You have to be aware that the ester in the startingmaterial can form amide.
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