[dani]

Hi, I found a  synthetic procedure for 3-aryl-coumarin in litterature (see image coumarin formation 1).
I would like to obtain the product in the image coumarin formation 2 through the similar procedure. I would like to introduce a boronic ester group to use the coumarin in a suzuki-miyura couplin with an aryl bromide. The question is, could the boronic ester inhibit the reaction? It is a lewis acid so it could be a catalyst for this reaction , but I am afraid that it could bound to the hydroxy group of the salicyl-aldehyde reagent inhibiting the reaction.
Thank you very much

[rolnor]

If the reaction on the top works, it seems probable that the bottom reaction should work. How do you plan to introduce the boronic substituent?

[dani]

Hi , thanks for your answer, I will buy the reagent, both boronic acid and pinacol boronic ester of phenilacetic acid are avalable.
so you think that my approach (coumarin formation 2 top image) could work and the final product could be used in a suzuki miyura coupling?

[rolnor]

Yes, what are you worried about could happen?

[dani]

I was worried about that my approach for cumarin synthesis (2 top reaction) with para-boronic pinacolester phenil acetic acid may not work