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Topic: Stability of ozonide  (Read 3415 times)

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Offline hypha

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Stability of ozonide
« on: February 23, 2007, 03:45:25 PM »
I have to run an ozone reaction at -75°C, then in a one pot process I have to reduce the aldehyde formed by NaBH4. This reduction step take place at -15°C/-10°C not lower. I would like to have some information regarding the stability (and the safety) of the ozonide formed. A run away is possible during the warm up between -75°C and -10°C. This reaction will be run in very large scale. Somebody has some background in this reaction?

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Re: Stability of ozonide
« Reply #1 on: February 23, 2007, 07:20:04 PM »
Secondary ozonides are usually okay as long as you don't concentrate them.  They can be explosive when they are concentrated though.  However, I have seen crystal structures of secondary ozonides!

You can probably warm the reaction to -10 degrees C safely (do it slowly though, don't just drop it into a -10 bath) and then add the borohydride.  You shouldn't have to concentrate it at all.

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