I'm not really familiar with the solubility.
How soluble are the tocopherols (mainly alpha and gamma, although they're quite similar) and fatty acids (ie. those found in nuts, etc) in methanol? I know that Vitamin E is fat-soluble, and that methanol is fully miscible in water, so I would infer that Vitamin E is not miscible in methanol. However, I know that this method of thinking isn't exactly accurate, so I'd like some help.
Also, on regular phase thin layer chromatography (TLC) plates, I separated an extract in 50% methanol, 50% ethyl acetate, with microliter amounts of acetic acid mixed in that system. If the compound/fraction traveled about half way up the regular phase plate, what is it's relative solubility? I know that it didn't move in hexane, so if I had to guess, I would say that it's really polar. However, I don't know the extent of the polarity relative to the used solvent.
Thanks.