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Topic: Drosophila melanogaster: mode of inheritance  (Read 12011 times)

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Offline Sev

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Drosophila melanogaster: mode of inheritance
« on: August 12, 2007, 07:10:28 AM »
Hi
I was hoping someone could help identify the mode of inheritance (recessive/dominant, sex-linked etc)in a Drosophila 'cross' I performed recently.

A wild type male was mated with a female with a 'curly wing' (mutant) phenotype.  The first (F1) progeny produced the two phenotypes in equal measure across the sexes (a quarter of the generation were male wild type, another quarter was male mutant, another was female wild type, and lastly female mutant).

This does not conform to the typical Mendelian ratios for F1 generation. 

Could someone kindly help identify the mode of inheritance for the mutant allele.

Thanks.

Offline Yggdrasil

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Re: Drosophila melanogaster: mode of inheritance
« Reply #1 on: August 12, 2007, 02:16:02 PM »
Maybe the curly wing allele is an autosomal dominant trait that is lethal when homozygous.  This would mean that your curly wing mutant is a heterozygote.

Offline Sev

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Re: Drosophila melanogaster: mode of inheritance
« Reply #2 on: August 12, 2007, 06:04:56 PM »
Thank you...your mode of inheritance does seem to explain my results.

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