[kimi85]

What is the product of the reaction of an alkyne with NaNH₂, NH₃, then CH₃I?

Thank you very much.

[sjb]

What is the product of the reaction of an alkyne with NaNH₂, NH₃, then CH₃I?

What kind of alkyne? I can see this perhaps going two ways, depending on whether you have an internal or terminal alkyne.

S

[kimi85]

it's a terminal alkyne

[Mr Peanut]

OK then,

With reguard to sodium amide the alkyne will behave like an acid forming a sodium acetylide and ammonia.

Sodium acetylides will react with primary RX to form R substituted alkynes.

[kimi85]

thank you.