[spirochete]

How many times should you expect to find a six base pair DNA sequence in a 11,000 BP fragment of DNA?

I am 90% lost on how to do this.  I feel like part of the answer should involve raising 0.25 to the sixth power, because that's the probability of finding a paticular sequence in six nucleotides.

[Martingale]

How many times should you expect to find a six base pair DNA sequence in a 11,000 BP fragment of DNA?

I am 90% lost on how to do this.  I feel like part of the answer should involve raising 0.25 to the sixth power, because that's the probability of finding a paticular sequence in six nucleotides.

1) Are A-T / T-A and G-C /C-G equally likely in a DNA molecule?

2) Are you allowing for overlaps?

If you allow for overlapping then the particular sequence you are looking for will have an effect on the expected value.

[spirochete]

I believe we can assume that AT/CG are equally likely, and I'm not sure if we're allowing for overlaps.  I think this is how the problem was supposed to be solved:

(O.25^6)(11,000) 

I'm not sure if this method accounts for overlaps.  It seems like it does.

[Martingale]

I believe we can assume that AT/CG are equally likely, and I'm not sure if we're allowing for overlaps.  I think this is how the problem was supposed to be solved:

(O.25^6)(11,000) 

I'm not sure if this method accounts for overlaps.  It seems like it does.

It does but it ignores the dependence between the overlaps