[MAFII]

I am attempting to do the Miyaura Borylation Reaction.  I have never done it so I have some questions.

What's the best Boron intermediate to use:

Bis pinacolato diboron

Catechol Borane

Second, what's the best way to make the Borate Ester from those groups?

Thank you for your help.

-M.

[boronic]

Hy. Then i was i Sheffield university i made boronic ester using bispinacolato diboron. This metod is very simple, but you need degass your mixture several times. Workup is simple to. Second way to get boronic ester is using BuLi. Disadvantage of this method - you should keep -78oC exact, because side reactions will go very well. If you want i can send to you procedure with bispinacolato diboron.

Sorry for my speech.

Boronic.

[MAFII]

Please do.

[D]

Hello,

I'm having problems with a miyaura reaction. My conditions are DMF at 80°C, with NaOAc as base.
As catalist I try to use (dppf)2PdCl2   under Argon.

It doesent reall seem to work. The reactive mediumturns black (decomposition of the catalyst?) and there remains a lot of starting arylbromide.

Can anybody guess what I am doing wrong?