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Topic: Lypholization  (Read 5677 times)

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Offline LabTech

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Lypholization
« on: April 15, 2008, 01:21:03 PM »
In the experimental section of some papers I have read, I have come across the term "lypholization."  I do not remember ever learning about that as an undergrad.  Could anybody explain to me what it is and what it is used for?
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Offline chiralic

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Re: Lypholization
« Reply #1 on: April 15, 2008, 01:34:13 PM »
Hi...

Read this on: http://en.wikipedia.org/wiki/Lypholize

Regards,

Chiralic
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Offline Shazza2008

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Re: Lypholization
« Reply #2 on: April 15, 2008, 03:42:33 PM »
This means freeze drying. An aqueous solution is shell frozen at -196 deg C (ie liquid nitrogen temperature) and then pumped on a vacuum manifold. This slowly removes the water and usually leaves a nice dry, fluffy solid.

S
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