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Topic: what's the difference between base and nucleophile ?  (Read 15932 times)

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Offline Mahmoud

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what's the difference between base and nucleophile ?
« on: January 01, 2009, 06:00:27 AM »
Hi all !

I'm very confused between base and nucleophile , what's the difference between them taking in mind i can distinguish when the reaction need base or nucleophile but when i say that's base or nucleophile regardless the type of reaction .

Thanks a lot 
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Offline Gregorian

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Re: what's the difference between base and nucleophile ?
« Reply #1 on: January 01, 2009, 12:01:11 PM »
bases abstract hydrogens and nucleophiles attack carbons (electrophiles)
all nucleophiles are bases, but not all bases can act as nucleophiles.
you should pay attention to steric that can prevent attacking carbon forcing the nucleophile to act as a base abstracting hydrogen
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Offline Mahmoud

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Re: what's the difference between base and nucleophile ?
« Reply #2 on: January 01, 2009, 12:16:53 PM »
Thanks
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Offline Ahmed Abdullah

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Re: what's the difference between base and nucleophile ?
« Reply #3 on: January 19, 2009, 01:05:08 AM »
Basicity is about equilibrium.
Nucleophilicity is about the rate.
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