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Topic: Synthesis problem: alkylation of benzene derivative  (Read 3038 times)

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Offline combatwombat

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Synthesis problem: alkylation of benzene derivative
« on: March 12, 2009, 02:08:38 AM »
You have 1,4-dimethoxybenzene and need to attach 2 t-butyl groups. What compounds besides t-butanol and t-butyl bromide (w/ a Lewis acid) could also work?
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Offline sjb

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Re: Synthesis problem: alkylation of benzene derivative
« Reply #1 on: March 12, 2009, 07:59:12 AM »
What's the synthon you need to attach a t-butyl group to the ring? How else can you make it?
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