[lutesium]

What are the reactions of these compounds??? Wiki says that they're electrophiles but can someone list me some reactions of them???


Thanks!!!

[lutesium]

Other than Edman Degradation please.


Lutesium...

[sjb]

What do you think some other reactions may be - and why not the Edman degradation? There are a few examples at wiki, for instance.

[lutesium]

Because a company that I know offers chemicals all based on IsothioCyanate structure! And I wondered what they could be used for??? Can they be converted into Amines, Alcohols, Aldehydes or into other functional groups??? Do PhenylIsoCyanates carry the same properties as Aliphatic Isocyanates???

[lutesium]

Any other comments???


Lutesium...

[nj_bartel]

not the safest compounds to just be messing around with...

[Markov]

Combine an amine with an isothiocyanate and you get a thiourea. Mop up the excess isothiocyanate with a scavenger and, bam, your compund is there. Quick and pure. This is a convenient way to make a small library of different thioureas.

Medicinal chemists tend to like stuff like this, hence some companies specialize in selling this type of reactive building blocks.