[Rakkoonn]

Hi,

I'm in a need to detect whether thiol endgroups are present in a copolymer resin that I modified with cysteamine - I need to confirm that it attached itself via the nitrogen atom. Prefereably with a chemical reaction. I guess it might not be easy. Any ideas? I'm going to search some publications later on today, but maybe someone already had a similar problem here. Thanks in advance

[doc30]

Raman spectroscopy would be the best way to go. It has a very high sensitivity to sulfur due to its high polarizability. Look for the S-H stretch around 2600 cm-1 and the C-S stretch in the ~700-600 cm-1 range. These bands are highly polarized and the C-S band position is also very sensitive to conformation variations around the adjacent C-C bond. Raman will also readily detect any disulfide formation.

Sulfur is fairly weak in the FT-IR since they do not have a strong dipole compared to other functional groups.

[Rakkoonn]

Thanks, I guess spectroscopy is the obvious and best choice, but we can't afford it, so chemical reactions are preffered. Found some interesting publications today, maybe that'l work

cheers, looking forward for more hints