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Topic: Glucocorticoids  (Read 3965 times)

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Offline kapital

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Glucocorticoids
« on: April 25, 2010, 06:18:14 AM »
Whay have Glucocorticoids antiinflamatory action?

Offline Wreath

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Re: Glucocorticoids
« Reply #1 on: May 03, 2010, 10:35:04 AM »
corticoids activates lipocortin, which lowers the level of phospholipase A2.
PLA2 is responsible for releasing arachidonate from phospholipids. arachidonate is a precurosor of eikosanoids (prostaglandines etc) which are involved in inflammatory reaction.

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