November 29, 2024, 05:46:36 AM
Forum Rules: Read This Before Posting


Topic: chlorination of phenols  (Read 3682 times)

0 Members and 1 Guest are viewing this topic.

Offline eunChae

  • Regular Member
  • ***
  • Posts: 25
  • Mole Snacks: +0/-0
chlorination of phenols
« on: May 18, 2010, 01:45:04 PM »
     How can I chlorinate phenol and get 2,3,5-trichlorophenol? Bromination is relatively easy but chlorination is problematic as I know. Any suggestion for starting?

Offline Grundalizer

  • Full Member
  • ****
  • Posts: 257
  • Mole Snacks: +19/-31

Offline orgopete

  • Chemist
  • Sr. Member
  • *
  • Posts: 2636
  • Mole Snacks: +213/-71
    • Curved Arrow Press
Re: chlorination of phenols
« Reply #2 on: May 18, 2010, 10:57:36 PM »
This looks like diazonium chemistry, so one route would be to start with a nitration.
Author of a multi-tiered example based workbook for learning organic chemistry mechanisms.

Sponsored Links