Yep. When I lived in Lexington, KY there were VERY few jobs that came up that were not your PhD level jobs. Maybe one every three months. End result essentially 2 yrs of unemployment. Talk about hard on your soul. When I moved to San Diego, California its VERY different. New jobs pop up on craigslists it seems daily. Many are entry level where you just need to have had some experience with techniques (ie familiar with running gels or protein purification). Some requrie 2 yrs experience. My particular job that I got requested someone with air-free chemistry experience and a materials science experience. It just so happens I had both, albeit much more air sensitive chem experience than materials science. Now I am in a job where I am salary (equiv to about $20/hr) which I got with no previous industrial experience in a great company (at least I really like working there). I will be finishing up my first year in April.
Also, on craigslist it is often a good idea to search for both chemist AND chemistry. Chemist search shows 12 jobs, chemistry shows 55.
Lastly, don't over restrict your field. My field was almost entirely pure inorganic synthesis (namely main block inorganics). I just did a bit of undergrad work in materials science and dabbled a bit in the lab with it. Now I make CdSe nanocrystals aka Quantum Dots in a biotech company where my boss and I are the only ones who do true chemistry.