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Topic: Can carboxylic acids catalyze their own reactions (such as synthesis of esters)?  (Read 2585 times)

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Offline Fzang

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Can carboxylic acids catalyze their own reactions (such as synthesis of esters)?
« on: February 28, 2011, 10:04:37 AM »
To start the ester synthesis you need to protonate the C=O group, and I was wondering if the acidic COOH proton of carboxylic acids could dissociate, only to protonate the C=O group on the same molecule (or most probably an identical, different molecule) instead?
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Offline discodermolide

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Re: Can carboxylic acids catalyze their own reactions (such as synthesis of esters)?
« Reply #1 on: February 28, 2011, 10:09:52 AM »
Quote from: Fzang on February 28, 2011, 10:04:37 AM
To start the ester synthesis you need to protonate the C=O group, and I was wondering if the acidic COOH proton of carboxylic acids could dissociate, only to protonate the C=O group on the same molecule (or most probably an identical, different molecule) instead?

Yes they can catalyse their own reactions.
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Offline Fzang

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Re: Can carboxylic acids catalyze their own reactions (such as synthesis of esters)?
« Reply #2 on: February 28, 2011, 10:12:41 AM »
Cool, thanks.
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