some questions regarding the synthesis:
1) Why is an acetyl group added to aniline (making acetanilide) and then removed to regenerate the amine group in sulfanilamide.
2) Acetic anhydride, like any anhydride, reacts with water to for a carboxylic acid. How then is it possible to carry out an acetylation in aqueos solution?
what is the purpose of the HCl and the sodium acetate in this reaction?
3) What happens when p-acetaminobenzenesulfonyl chloride is allowed to stand for some time in contact with water?
(i'll get a pic of the rxn up soon)
we carried out this synthisis in the lab so if you need to know any of the conditions or reagents just ask