[peptideismylife]

Hey guys!

I am going to carry out a chemical reaction. In the protocol they are using 900mg of the starting material and 4.3ml of water as well as 7.2ml of DCM. I want to do the same reaction but using 100 mg (1/9part) of the starting material...it means that I have to use 1/9 of the solvents, that is 0.47 ml of water and 0.8ml of DCM?

[Dan]

If you want to replicate the conditions then yes, you would want 4.8 mL of water (note 4.3/9 = 0.48 not 4.7) and 0.80 mL DCM.

The precise concentration you use is not usually critical though, the reaction will probably still work fine (but slower) at higher dilution.