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Topic: Resolution of 1,2-diaminocyclohexane  (Read 5741 times)

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Offline sundberg

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Resolution of 1,2-diaminocyclohexane
« on: October 11, 2005, 10:47:08 AM »
Hi!
I need the mechanism for resolution of racemic 1,2-diaminocyclohexane using L-(+)-tartaric acid.
It's for a report for a student lab we did, but I can't find any information about the mechanism and I've searched journals, textbooks and Google. Any pointers and tips are appreciated!

/Jonas

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Re:Resolution of 1,2-diaminocyclohexane
« Reply #1 on: October 11, 2005, 03:58:06 PM »
Not much of a mechanism to be had.  It forms a bis-ammonium salt through simple acid-base chemistry.  The resolution occurs because the two possible salts are diastereomeric and one crystallizes much more readily than the other.

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