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Topic: EAS Lab Question  (Read 3392 times)

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Offline aspiringphysician

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EAS Lab Question
« on: June 06, 2012, 12:30:31 AM »
Hello all,

I was wondering: does 3-phenylpropanoyl chloride react with AlCl3 to form 1-indanone?

Thanks muchly  ;D

AP
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Offline Nosterius

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Re: EAS Lab Question
« Reply #1 on: June 06, 2012, 07:53:38 AM »
How can an acyl chloride + AlCl3 react with an aromatic molecule?

How about this reaction being done intramolecularly?
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Offline aspiringphysician

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Re: EAS Lab Question
« Reply #2 on: June 09, 2012, 02:50:18 PM »
Quote from: Nosterius on June 06, 2012, 07:53:38 AM
How can an acyl chloride + AlCl3 react with an aromatic molecule?

How about this reaction being done intramolecularly?

Thanks for your response! That's exactly what I was thinking...so it would form another ring, correct?

Similarly, would 4-Chloro-1-phenyl-1-butanol react with NaOH in an intramolecular SN2 reaction to form a cyclic ether? Would stereochemistry be relevant in this case?
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