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Topic: Help with specific rotation of a tetrasaccharide  (Read 1806 times)

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Offline john2520

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Help with specific rotation of a tetrasaccharide
« on: October 04, 2012, 09:51:07 PM »
The specific rotation of a tetrasaccharide was measured to be -20.5. Upon complete hydrolysis in acid the optical rotation of the solution was found to be -36.9. Know that the specific rotation of N-acetyl-glucosamine (-105), 4-methoxy-D-mannose (14.2), and 2-deoxy-D-ribose (18.7) what would be the specific rotation of the last monosaccharide unit, 3-deoxy-l-fucose.

So I was thinking we completely ignore the -20.5 and just total the 4 monosaccharide units to 36.9.

-105+14.2+18.7+x = -36.9 and then solve for x but i dont think its suppost to be that simple, can anyone give me any insight on what to do.

Offline Dan

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Re: Help with specific rotation of a tetrasaccharide
« Reply #1 on: October 05, 2012, 03:08:24 AM »
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i dont think its supposed to be that simple

It is almost that simple. You've got the right idea, -36.9 is the average (note: not the sum) rotation of the four equimolar monosaccharides.
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