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Topic: Substitution and Elimination reactions and favorability  (Read 1479 times)

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Offline Woopy

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Substitution and Elimination reactions and favorability
« on: October 30, 2012, 01:48:10 AM »
Hello,

I am not sure why protic solvents favor E1 and SN1 reactions, whereas aprotic solvents favor E2 and SN2 reactions. I just memorize, but I wanted to know some reason that I can grasp so I don't have to memorize and can just rationalize it.

Also, what are strong nucleophiles that are weak bases?
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Offline discodermolide

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Re: Substitution and Elimination reactions and favorability
« Reply #1 on: October 30, 2012, 03:11:17 AM »
Think about the differences in mechanism between the two reaction types. Which reaction types involve charges and how could these charges interact with the solvents?
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