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Topic: Need Help with understanding a Synthesis  (Read 1708 times)

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Offline ignorantsage

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Need Help with understanding a Synthesis
« on: December 10, 2012, 09:54:06 PM »
See link below

http://i.imgur.com/aEs8r.png

I know this forms but I dont know where to go from here, I assume an enolate forms as well, both look like electrophiles to me :\

http://i.imgur.com/bt7Ek.jpg
« Last Edit: December 10, 2012, 10:19:39 PM by Arkcon »

Offline Dan

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Re: Need Help with understanding a Synthesis
« Reply #1 on: December 11, 2012, 04:44:36 AM »
What happens if you mix a primary amine with an aldehyde:

primary amine + aldehyde  :requil: ?

How will this product ? interact with an enolate.

Quote
I assume an enolate forms as well, both look like electrophiles to me

An enolate is not an electrophile - the fact that it is anionic should immediately tell you that.

Note: This first step is a very classical named reaction.
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