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Topic: D2O  (Read 4263 times)

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Offline kapital

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D2O
« on: January 30, 2013, 10:54:22 AM »
I know when we add D2O basic and acid protons disappear from 1H spectrum, due to change, but  what happen when some peaks change their chemical shift, when a D2O is added to sample?

Offline discodermolide

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Re: D2O
« Reply #1 on: January 30, 2013, 11:44:15 AM »
Perhaps you added too much, 1 drop is all you need.
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Offline kapital

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Re: D2O
« Reply #2 on: January 31, 2013, 02:03:45 AM »
No I did not mean practically, I meant theoretically. I saw some exercises, where it says peak change chemical shift after D2O is added.

Offline discodermolide

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Re: D2O
« Reply #3 on: January 31, 2013, 02:17:22 AM »
Well if the NMR solvent is water miscible then I would expect a shift in the signal.
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Re: D2O
« Reply #4 on: January 31, 2013, 04:07:07 AM »
So the acid base peaks are only ones, besides solvent, that can change, when D2O is added to sample?

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Re: D2O
« Reply #5 on: January 31, 2013, 04:21:07 AM »
No. The shifts in methanol and methanol/ water will be slightly different
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