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Topic: Need to make an Alkyne  (Read 2159 times)

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Offline Nescafe

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Need to make an Alkyne
« on: February 16, 2013, 04:35:55 PM »
Hi,

So I need to make an alkyne in lab and I have a few options as starting material. Which one is the easiest to start with?  Basically I need to synthesize 1-cyclohexyl-4-ethynylbenzene and I can start with either one of these readily available SMs.

Cyclohexylbenzoic acid
(4-cyclohexylphenyl)methanol
or 4'-Cyclohexylacetophenone

I know for alkynes you typically need bromine usually for bromination but I was wondering if there are any alternatives I might not know about.

Thanks,

Nescafe.

Offline AWK

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Re: Need to make an Alkyne
« Reply #1 on: February 16, 2013, 06:41:07 PM »
In one of the above compounds you have a complete carbon skeleton
AWK

Offline Nescafe

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Re: Need to make an Alkyne
« Reply #2 on: February 16, 2013, 08:39:54 PM »
In one of the above compounds you have a complete carbon skeleton

Okay, not very helpful though, but thanks! =)

Offline Dan

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Re: Need to make an Alkyne
« Reply #3 on: February 17, 2013, 05:24:22 AM »
Okay, not very helpful though

Put some effort in yourself. Get a book off the shelf or google alkyne synthesis. You have been here long enough to know that we are not going to drop the answer in your lap (Forum Rules).
My research: Google Scholar and Researchgate

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