Topic: Thiamin oxidation to Thiochrome? (Read 5801 times)

araffe · « **on:** February 01, 2006, 08:30:21 AM »

Does any one know the mechanism of the Thiamin oxidation to Thiochrome with Fe(CN)6

AWK · « **Reply #1 on:** February 01, 2006, 09:22:28 AM »

Generally, oxidtion mexchanisms are difficult for a detailed explanation.
Thiamine can be oxidised to thiochrome by numerous mild oxidisers,
eg Hg2+, H2O2 or ferricyanide anion.
May be this link put some light on this problem
http://www.jobinyvon.com/usadivisions/Fluorescence/applications/F-07_App_Note_Vitamin_B1.pdf