[kamikaze]

Hello, I'd like to know the optical relationship between R and S enantiomer (assuming that the compound has one stereocenter). That is, for example, if an optical rotation of R enantiomer is -28, then what would be the optical rotation of S enantiomer? Any suggestions or hints would be greatly appreciated, thanks

[discodermolide]

If you know that the (R) enantiomer has a rotation of -28° then the (S) enantiomer should be +28°.

But note, unless you measure the rotation there is no relationship between the (R) and (S) configuration and optical rotation.