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Topic: Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman  (Read 1794 times)

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Offline SethFlanders

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Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman
« on: March 19, 2013, 10:14:06 PM »
I have continued working on my unknown project and I have hit a point where I need outside input.  I am trying to figure out the named reaction mechanism for the synthesis of 2-oxochroman from 3-2-(hydroxyphenyl)-propanoic acid using Ph3P, DEAD, and THF.  I think the named reaction might be the Corey-Nicolaou Macrolactonization but I am unsure. 
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Offline discodermolide

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Re: Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman
« Reply #1 on: March 19, 2013, 10:16:39 PM »
Is that not the Mitsunobo macrolactonisation?
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Offline SethFlanders

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Re: Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman
« Reply #2 on: March 19, 2013, 10:25:09 PM »
Hmm.  I believe you are right.  Is that the name of a reaction then?  I am new to named reactions.
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Offline SethFlanders

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Re: Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman
« Reply #3 on: March 19, 2013, 10:26:13 PM »
Oh that is!  Thank you very much.  Now I have to just finish my presentation.  I can't give you enough snacks for your help.
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Offline discodermolide

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Re: Named Reaction for 3-2-(hydroxyphenyl)-propanoic acid to 2-oxochroman
« Reply #4 on: March 19, 2013, 10:36:48 PM »
My pleaure ;D
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