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Topic: Oxidation in the Presence of Cycloheptatriene Unit  (Read 1449 times)

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Offline BADGES

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Oxidation in the Presence of Cycloheptatriene Unit
« on: March 20, 2013, 01:11:44 PM »
I'm trying to oxidize a methyl group on a aryl ring but attached to my aryl ring is a cycloheptatriene unit.  Is this possible or will the cycloheptatriene be oxidized before the methyl?

All literature I find about the oxidation of cycloheptatriene has it unsubstituted so I'm not sure how the substitution will affect it.

Offline discodermolide

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Re: Oxidation in the Presence of Cycloheptatriene Unit
« Reply #1 on: March 20, 2013, 01:16:24 PM »
I suppose you are using quite a strong oxidant? If that is the case then the cycloheptatriene unit will also be oxidised. See
http://pubs.acs.org/doi/abs/10.1021/ja00816a028

That is only the first page but it gives an indication.
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