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Topic: Conversion of benzoic acid to benzyl alcohol using NaBH4  (Read 7841 times)

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Offline shahrukhsun

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Conversion of benzoic acid to benzyl alcohol using NaBH4
« on: September 10, 2013, 08:37:36 AM »
I want to convert benzoic acid to benzyl alcohol using sodium borohydride. I have found one method using (sodium borohydride+boron triflorodiethyl etherate). Boron triflorodiethyl etherate found very costly. Is there any cheap substitute of Boron triflorodiethyl etherate for this type of reaction?
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Offline discodermolide

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Re: Conversion of benzoic acid to benzyl alcohol using NaBH4
« Reply #1 on: September 10, 2013, 08:51:45 AM »
You can easily make the methyl ester then reduce that with sodium borohydride in methanol/THF at 55°C.
The alternative is BH3.DMS at reflux on benzoic acid.
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Offline cbn

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Re: Conversion of benzoic acid to benzyl alcohol using NaBH4
« Reply #2 on: September 11, 2013, 02:25:44 AM »
you can use LiAlH4 alternatively for reduction of benzoic acid to benzyl alcohol.
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Offline clarkstill

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Re: Conversion of benzoic acid to benzyl alcohol using NaBH4
« Reply #3 on: September 11, 2013, 05:34:46 AM »
Or generate borane in situ using NaBH4 and iodine...
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