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Topic: Glutathione  (Read 2544 times)

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Offline biogod4235

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Glutathione
« on: February 23, 2014, 09:10:38 PM »
Trying to figure out how to draw it in Zwitterion form. Right now I have what's below. What is wrong with it?
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Offline Benzene

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Re: Glutathione
« Reply #1 on: February 23, 2014, 09:25:18 PM »
What do you know about amides?
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Offline biogod4235

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Re: Glutathione
« Reply #2 on: February 23, 2014, 09:34:33 PM »
Quote from: Benzene on February 23, 2014, 09:25:18 PM
What do you know about amides?

Carbon double bonded to an oxygen and single bonded to a nitrogen.
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Offline AlphaScent

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Re: Glutathione
« Reply #3 on: February 24, 2014, 12:32:52 PM »
Are you at a biological pH? 

http://en.wikipedia.org/wiki/Glutathione

What is wrong, based on this structure?  Your pH is going to affect whether it is a zwitterion or not.
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If you're not part of the solution, then you're part of the precipitate

Offline Babcock_Hall

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Re: Glutathione
« Reply #4 on: February 24, 2014, 01:24:18 PM »
In addition to other issues, I would also look into typical pKa values for thiol groups.
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