Chemical Forums
1 Hour
1 Day
1 Week
1 Month
Forever
December 26, 2024, 01:35:42 PM
Forum Rules
: Read This Before Posting
Home
Help
Search
Login
Register
Chemical Forums
Chemistry Forums for Students
Organic Chemistry Forum
Organic Chemistry Forum for Graduate Students and Professionals
Sulfa-Michael Addition of a thiol to an enone.
« previous
next »
Print
Pages: [
1
]
Go Down
Topic: Sulfa-Michael Addition of a thiol to an enone. (Read 2754 times)
0 Members and 1 Guest are viewing this topic.
OrganicBanana
Very New Member
Posts: 1
Mole Snacks: +0/-0
Sulfa-Michael Addition of a thiol to an enone.
«
on:
May 21, 2014, 01:46:06 PM »
Hello, I am stuck on a step in my total synthesis on how to preform an enantioselective thiol addition of β-mercaptolactate to α,β-unsaturated Dehydrocurvularin species at the four position with R configuration. Thank you for your time.
Logged
discodermolide
Chemist
Sr. Member
Posts: 5038
Mole Snacks: +405/-70
Gender:
Re: Sulfa-Michael Addition of a thiol to an enone.
«
Reply #1 on:
May 21, 2014, 01:47:49 PM »
Try an organocatalytic reaction with proline or the like as a chiral base.
Plenty of literature out there for this sort of reaction.
Logged
Development Chemists do it on Scale, Research Chemists just do it!
My Research History
Print
Pages: [
1
]
Go Up
« previous
next »
Sponsored Links
Chemical Forums
Chemistry Forums for Students
Organic Chemistry Forum
Organic Chemistry Forum for Graduate Students and Professionals
Sulfa-Michael Addition of a thiol to an enone.