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Topic: Solutions from tabs  (Read 2401 times)

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Offline prosolutions

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Solutions from tabs
« on: May 09, 2014, 02:27:18 PM »
Hello all,
I'll start studying pharmacy BSc this year and I'm so excited. Well, first two years will surely be more boring than the 3rd with more practical experiments. I'm actually very knowledgeable concerning medicaments and I'm now looking for doing some solutions, as my name indicates.

But here's my problem. Given paracetamolum and you want to make a liquid form of it how do you know which substances you can take for it? Can you take ethanol or not? I guess this is for every substance different?! Is there something like a step-by-step-introduction on doing liquids with chemicals?
Thanks in advance:)

Offline Polytriazole

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Re: Solutions from tabs
« Reply #1 on: May 21, 2014, 10:16:01 PM »
If you look up a solid chemical in a Merck Index or a CRC handbook (or, sometimes, on Wikipedia, though I would confirm anything I found on the Wiki with a more reputable source like Merck or CRC) you can generally find information on solubility.  Usually this will just tell you what it's miscible, soluble, or insoluble in, which is a good place to start.  For more specific solubility information, you will need to consult the literature or a technical handbook.  Both the Merck Index and the CRC Handbook should be available at your library.

Worse come to worst, if you are in lab, you can always do a quick solubility assay yourself with a rack of test tubes, small amounts of the solid, and small amounts of the solvents you have available.  I did that a couple times during grad school because I was working with compounds with no reported solubility information.

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