[faust]

Hello,

Just a simple question, do you know what is the mechanism for the N-boc deprotection using phenol and tmscl?


Thank you very much

[movies]

The carbonyl oxygen attacks TMS, then the t-butyl carbocation falls off and gets trapped by the phenol to make t-butyl phenyl ether.  The TMS carbamate decomposes in in water to make CO₂ and TMS-OH.