[Jackwill]

So I need to design the heating and cooling system for a batch plant (pharmaceuticals).

Majority of the unit operations are jacketed vessels (reactors, filters etc.)
How can I heat up and cool down a single operation?
For example, I need to heat up 'reactor 1' to 100 degrees then gradually cool it down to -10 degrees.
I was thinking of using dowfrost as the heat transfer fluid as it has a big temperature range so could do both, but how exactly would the dowfrost be heated up to 100 degrees?

For the cooling process some sort of chiller/fridge could be used.

Are there better options I haven't thought of?

Beginner chemical engineering student so please spare my lack of knowledge.
 
Kind regards
J. Will