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Topic: Reverse reaction  (Read 1904 times)

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Offline sun725

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Reverse reaction
« on: March 23, 2017, 06:47:49 PM »
So, they want us perform a reverse reaction, where carboxylic acid is reduced to aldehyde and how we would do that. Do they want us to draw the mechanism or just explain how we can obtain that?
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Offline Babcock_Hall

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Re: Reverse reaction
« Reply #1 on: March 23, 2017, 09:54:50 PM »
Your question is very open-ended.  Is this for an organic chemistry class or laboratory or a biochemistry class?  The reduction of a carboxylic acid to an aldehyde is not trivial, but it has been discuss in threads here previously.
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Offline rolnor

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Re: Reverse reaction
« Reply #2 on: March 24, 2017, 09:38:26 AM »
To do it in twoo steps, first convert acid to acidchloride, then use tributyltin hydride.
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Offline discodermolide

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Re: Reverse reaction
« Reply #3 on: March 25, 2017, 01:24:36 PM »
Hydrogenation is better: Rosenmund reduction. Avoids using toxic tin compounds.
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