November 27, 2024, 11:33:08 AM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: Epoxide opening with dimethylamine  (Read 2565 times)

0 Members and 1 Guest are viewing this topic.

Offline Bakterien

  • Regular Member
  • ***
  • Posts: 33
  • Mole Snacks: +0/-0
Epoxide opening with dimethylamine
« on: January 10, 2018, 09:45:14 AM »
Tried to open cyclohexene oxide with dimethylamine (2M i THF) but no conversion after 24 at 60 C.
Any suggestions ? Lewis acids ?
Logged

Offline wildfyr

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 1776
  • Mole Snacks: +203/-10
Re: Epoxide opening with dimethylamine
« Reply #1 on: January 10, 2018, 12:24:58 PM »
Hmm that is a bit odd. This paper on using Lewis acid catalysts to ring open epoxides with alkyl amines might be useful


https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2004-817780
Logged
Pages: [1]   Go Up
« previous next »
Sponsored Links