[foxthreefour]

In a substitution reaction between a bromo-ketone and Methylamine would the Methylamine have preference when there is a potential mixture of Ammonia in the solution? If so is it likely that the ammonia will affect the reaction?

[wildfyr]

This has a potential to be rather messy since either one can make dimers as well. I think yes, there will be a product mixture regardless. This answer is based on pure gut, I don't have data to back it up. Methylamine should dominate if the two are equimolar, it is a better nucleophile.

[foxthreefour]

This has a potential to be rather messy since either one can make dimers as well. I think yes, there will be a product mixture regardless. This answer is based on pure gut, I don't have data to back it up. Methylamine should dominate if the two are equimolar, it is a better nucleophile.

Ok, thank you.