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Topic: synthesis (Read 3329 times)
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double_bond
Regular Member
Posts: 10
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synthesis
«
on:
July 07, 2006, 02:22:52 PM »
;hi..all
reaction between o-Phenylendiamine and formic acid yield benzimidazole ,can we use other aromatic acid insted of formic acid to get substituted imidazole. please give your valuable suggestions to perform the reaction between o-Phenylendiamine and salicylic acid.
here is the reference
Org. Syn. Coll. Vol. 2, 501
http://orgsyn.org/orgsyn/default.asp?formgroup=basenpe_form_group&dataaction=db&dbname=orgsyn
clik the link and type
benzimidazole
then you get the preperation of benzimidazole
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DavidW
Chemist
Regular Member
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Re: synthesis
«
Reply #1 on:
July 07, 2006, 06:49:01 PM »
You might want to check this reference out:
Journal of Hetereocyclic Chemistry, 1981, 18(4), 803-5.
They have procedures for the reaction between o-phenylenediamine and salicylic acid to form the corresponding benzimidazole
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