[Michele]

Hi
I'm new to this forum. I was searching some articles with reaction conditions in order to do an N-deprotection. I have a nitrone and after the reaction with a dipolarophile i need to remove the tert-butyl group on nitrogen. I've already tried with tons of TFA but it doesn't works. Any ideas? Could you please tell me some articles where this reaction is performed? Every substrate it's fine, it doesn't need to be necessary a nitrone. Thank you.

[AWK]

Simply google:
tert-butyl on nitrogen deprotection

[Michele]

Simply google:
tert-butyl on nitrogen deprotection

thank you, but it is mostly on esters while i need nitrogen. for this reason i asked here, maybe someone already had this problem.

[AWK]

You have probably read another publication?

[Michele]

You have probably read another publication?

I said mostly. In fact i saw this reaction and probably i will try it. The main problem i have is that i don't have a chelating group on my substrate.