[isshin]

The bottle contains 100mL of a solution labelled as phosgene solution 15wt. % in toluene. I need 5mmol of phosgene, which equals to 0.4946g. So, I am wondering how much solution should I draw up from the bottle to have 0.4946g of phosgene? The density of the entire solution displayed on the bottle is 0.924 g/mL

[Corribus]

It means the solution is 15 % by weight of phosgene. I.e., if you were to weigh out 100 g of the solution, 15 g would be phosgene and 85 g would be solvent.

[wildfyr]

Gotta say, I'm kind of terrified for someone who doesn't know how to sort this out on their own to be handling a phosgene solution. It is REALLY hazardous stuff, and that sort of calculation is something an experienced organic chemist does 3x a day.

[rolnor]

Yes, it was used as chemical weapon in ww2.

[hollytara]

I have worked with phosgene.  It is not to be trifled with.  You can inhale a lethal amount and not know it until the symptoms begin a day or so later.  If you are uncertain about these things, be sure and get someone experienced to help you.

[rolnor]

You can use triphosgene in most cases, this material is a solid and easy to handle. Fumehood is always necessary.