September 18, 2024, 09:29:14 PM
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Topic: Isolation of Boronic Acid  (Read 253 times)

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Offline yetyet

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Isolation of Boronic Acid
« on: September 10, 2024, 05:19:53 AM »
Hi, I am an undergraduate student conducting research on Suzuki-Miyaura polymerization.

After synthesizing the monomer by in-situ trapping, which is OHex, B(OH)2 and Br to the benzene ring. I have trouble in isolating the product as I can't fully extract the product using organic solvent from the mixture as I can always detect somthing (assuming the product since it is a boronic acid) on TLC plate. I tried Et2O and AcOEt but I still have the same problem.

If anyone have any idea how with this, it would help me a lot. Thank you!

Offline rolnor

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Re: Isolation of Boronic Acid
« Reply #1 on: Today at 05:20:31 AM »

I dont understand what compound you are making. It sounds like an interesting project. Do you have a reference you are using, a paper? To isolate boronic acids can probably be a bit tricky, boron is different and can behave strangely.

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