[NATO]

I do know that semicarbazide(aminourea) react with formic acid to form 1,2,4-triazol-3-one (1:1 molar ratio). Will carbohydrazide (diaminourea) react the same way to form amino-triazolone? Could tetrazinone be formed instead of amino-triazolone ?

Carbohydrazide cyclocondensate with aldehydes to form tetrazines



Will Carbohydrazide react with formaldehyde to form 1,2,4,5-tetrazine-3-one ?

[rolnor]

Two nitrogens on the same sp3 carbon is not very stable, its like an aminal. I dont think this will happen spontaneously, maybe you can force this somehow.

[NATO]

After searching it a bit, amiNes like to react with C=O bonds, forming -N=C- +H2O while amiDes react with -OH bonds forming -NH-C- +H2O. So CHZ with formic acid will for sure react with the amine forming O=C-(NH-NH2)-(NH-N=CH-OH). Now the -OH group will not react with the second amiNe group (-NH3). If it will, it will react with the amiDe (-NH-) group closing the ring, forming amino-triazol-one. Now the point is, how reactive the -NH group going to be with the -OH group ? In the case of semicarbazide, the amiDe group is a primary amiDe, easily reacting with the -OH group forming -NH-C- and clozing the ring, but in the case of CHZ, one H is replaced with the amiNe group, making the amiDe less reactive right ?

[rolnor]

I am not sure that I follow, the molecule you have as product is not stable I think, not on silica-tlc, and I doubt it will form at all, you could search Reaxsys or Casreact and see if you can make these compounds

[NATO]

How Reaxsys or Casreact works ? I could not figured out.

[rolnor]

You need an account, maybe you can use it on your university?

https://web.cas.org/marketing/pdf/casreactug.pdf#:~:text=Chapter%201:%20Overview%20of%20CASREACT%20Content%20Chemical%20Abstracts%20Reaction%20Search