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Topic: Nucleophilicity of Carbon anion  (Read 3132 times)

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Offline Butyllithium

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Nucleophilicity of Carbon anion
« on: January 06, 2008, 01:51:42 AM »
Hi, all,
In the following reaction, a nucleophilic addition reaction between carbon anions prepared in situ and acetone was figured. I want to know the nucleopilicity of this kind of carbonanion via de-silication type reaction in situ. And some kind of electrophilic group, such as lactones,esters,cyanides,imides, or other electrophilic reagents can tolerate it?
Thanks in advance.

Butyllithium

Offline Kryolith

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Re: Nucleophilicity of Carbon anion
« Reply #1 on: January 06, 2008, 05:14:17 AM »
Do you have an excess of TBAF to determine the kinetics? Which solvent do you use?

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